Search Results - Ahfeldt, Tim

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease by Coccia, Elena, Ahfeldt, Tim

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Drug discovery using neurons derived from patients: Studying Human Disease Using Human Neurons by Ahfeldt, Tim, Litterman, Nadia K., Rubin, Lee L.

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Modeling the complex genetic architectures of brain disease. by Fernando, Michael B., Ahfeldt, Tim, Brennand, Kristen J.

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Induced pluripotent stem (iPS) cells: an up-to-the-minute review by Lau, Frank, Ahfeldt, Tim, Osafune, Kenji, Akustsu, Hidenori, Cowan, Chad A

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A high efficiency system for the generation and study of human induced pluripotent stem cells by Maherali, Nimet, Ahfeldt, Tim, Rigamonti, Alessandra, Utikal, Jochen, Cowan, Chad, Hochedlinger, Konrad

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High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells by Sarrafha, Lily, Parfitt, Gustavo M., Reyes, Ricardo, Goldman, Camille, Coccia, Elena, Kareva, Tatyana, Ahfeldt, Tim

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Differentiation stage determines reprogramming potential of hematopoietic cells into iPS cells by Eminli, Sarah, Foudi, Adlen, Stadtfeld, Matthias, Maherali, Nimet, Ahfeldt, Tim, Mostoslavsky, Gustavo, Hock, Hanno, Hochedlinger, Konrad

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Temporal Proteomics During Neurogenesis Reveals Large-scale Proteome and Organelle Remodeling via Selective Autophagy by Ordureau, Alban, Kraus, Felix, Zhang, Jiuchun, An, Heeseon, Park, Sookhee, Ahfeldt, Tim, Paulo, Joao A., Harper, J. Wade

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Disease-specific induced pluripotent stem (iPS) cells by Park, In-Hyun, Arora, Natasha, Huo, Hongguang, Maherali, Nimet, Ahfeldt, Tim, Shimamura, Akiko, Lensch, M. William, Cowan, Chad, Hochedlinger, Konrad, Daley, George Q.

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Efficient Culturing and Genetic Manipulation of Human Pluripotent Stem Cells by Schinzel, Robert T., Ahfeldt, Tim, Lau, Frank H., Lee, Youn-Kyoung, Cowley, Alicia, Shen, Tony, Peters, Derek, Lum, David H., Cowan, Chad A.

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Pattern Specification and Immune Response Transcriptional Signatures of Pericardial and Subcutaneous Adipose Tissue by Lau, Frank H., Deo, Rahul C., Mowrer, Gregory, Caplin, Joshua, Ahfeldt, Tim, Kaplan, Adam, Ptaszek, Leon, Walker, Jennifer D., Rosengard, Bruce R., Cowan, Chad A.

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Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs by Mou, Hongmei, Zhao, Rui, Sherwood, Richard, Ahfeldt, Tim, Lapey, Allen, Wain, John, Sicilian, Leonard, Izvolsky, Konstantin, Lau, Frank H., Musunuru, Kiran, Cowan, Chad, Rajagopal, Jayaraj

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Dynamics of PARKIN-dependent mitochondrial ubiquitylation in induced-neurons and model systems revealed by digital snapshot proteomics by Ordureau, Alban, Paulo, Joao A., Zhang, Wei, Ahfeldt, Tim, Zhang, Jiuchun, Cohn, Erin F., Hou, Zhonggang, Heo, Jin-Mi, Rubin, Lee L., Sidhu, Sachdev S., Gygi, Steven P., Harper, J. Wade

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Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons by Ahfeldt, Tim, Ordureau, Alban, Bell, Christina, Sarrafha, Lily, Sun, Chicheng, Piccinotti, Silvia, Grass, Tobias, Parfitt, Gustavo M., Paulo, Joao A., Yanagawa, Fumiki, Uozumi, Takayuki, Kiyota, Yasujiro, Harper, J. Wade, Rubin, Lee L.

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells using synthetic modified mRNA by Warren, Luigi, Manos, Philip D., Ahfeldt, Tim, Loh, Yuin-Han, Li, Hu, Lau, Frank, Ebina, Wataru, Mandal, Pankaj, Smith, Zachary D., Meissner, Alexander, Daley, George Q., Brack, Andrew S., Collins, James J., Cowan, Chad, Schlaeger, Thorsten M., Rossi, Derrick J.

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Programming human pluripotent stem cells into white and brown adipocytes by Ahfeldt, Tim, Schinzel, Robert T., Lee, Youn-Kyoung, Hendrickson, David, Kaplan, Adam, Lum, David H., Camahort, Raymond, Xia, Fang, Shay, Jennifer, Rhee, Eugene P., Clish, Clary B., Deo, Rahul C., Shen, Tony, Lau, Frank H., Cowley, Alicia, Mowrer, Greg, Al-Siddiqi, Heba, Nahrendorf, Matthias, Musunuru, Kiran, Gerszten, Robert E., Rinn, John L., Cowan, Chad A.

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Characterization of Bipolar Disorder Patient-Specific Induced Pluripotent Stem Cells from a Family Reveals Neurodevelopmental and mRNA Expression Abnormalities by Madison, Jon M., Zhou, Fen, Nigam, Aparna, Hussain, Ali, Barker, Douglas D., Nehme, Ralda, van der Ven, Karlijn, Hsu, Jenny, Wolf, Pavlina, Fleishman, Morgan, O’Dushlaine, Colm, Rose, Sam, Chambert, Kimberly, Lau, Frank H., Ahfeldt, Tim, Rueckert, Erroll H., Sheridan, Steven D., Fass, Daniel M., Nemesh, James, Mullen, Thomas E., Daheron, Laurence, McCarroll, Steve, Sklar, Pamela, Perlis, Roy H., Haggarty, Stephen J.

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A TALEN genome editing system to generate human stem cell-based disease models by Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A. K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, Marta, Gupta, Rajat M., Moisan, Annie, Banks, Eric, Friesen, Max, Schinzel, Robert T., Xia, Fang, Tang, Alexander, Xia, Yulei, Figueroa, Emmanuel, Wann, Amy, Ahfeldt, Tim, Daheron, Laurence, Zhang, Feng, Rubin, Lee L., Peng, Lee F., Chung, Raymond T., Musunuru, Kiran, Cowan, Chad A.

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus by Musunuru, Kiran, Strong, Alanna, Frank-Kamenetsky, Maria, Lee, Noemi E., Ahfeldt, Tim, Sachs, Katherine V., Li, Xiaoyu, Li, Hui, Kuperwasser, Nicolas, Ruda, Vera M., Pirruccello, James J., Muchmore, Brian, Prokunina-Olsson, Ludmila, Hall, Jennifer L., Schadt, Eric E., Morales, Carlos R., Lund-Katz, Sissel, Phillips, Michael C., Wong, Jamie, Cantley, William, Racie, Timothy, Ejebe, Kenechi G., Orho-Melander, Marju, Melander, Olle, Koteliansky, Victor, Fitzgerald, Kevin, Krauss, Ronald M., Cowan, Chad A., Kathiresan, Sekar, Rader, Daniel J.

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Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells by Navarro, Elisa, Udine, Evan, de Paiva Lopes, Katia, Parks, Madison, Riboldi, Giulietta, Schilder, Brian M., Humphrey, Jack, Snijders, Gijsje J. L., Vialle, Ricardo A., Zhuang, Maojuan, Sikder, Tamjeed, Argyrou, Charalambos, Allan, Amanda, Chao, Michael J., Farrell, Kurt, Henderson, Brooklyn, Simon, Sarah, Raymond, Deborah, Elango, Sonya, Ortega, Roberto A., Shanker, Vicki, Swan, Matthew, Zhu, Carolyn W., Ramdhani, Ritesh, Walker, Ruth H., Tse, Winona, Sano, Mary, Pereira, Ana C., Ahfeldt, Tim, Goate, Alison M., Bressman, Susan, Crary, John F., de Witte, Lotje, Frucht, Steven, Saunders-Pullman, Rachel, Raj, Towfique

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