Výsledky vyhledávání - Ahfeldt, Tim

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease Autor Coccia, Elena, Ahfeldt, Tim

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Drug discovery using neurons derived from patients: Studying Human Disease Using Human Neurons Autor Ahfeldt, Tim, Litterman, Nadia K., Rubin, Lee L.

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Modeling the complex genetic architectures of brain disease. Autor Fernando, Michael B., Ahfeldt, Tim, Brennand, Kristen J.

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Induced pluripotent stem (iPS) cells: an up-to-the-minute review Autor Lau, Frank, Ahfeldt, Tim, Osafune, Kenji, Akustsu, Hidenori, Cowan, Chad A

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A high efficiency system for the generation and study of human induced pluripotent stem cells Autor Maherali, Nimet, Ahfeldt, Tim, Rigamonti, Alessandra, Utikal, Jochen, Cowan, Chad, Hochedlinger, Konrad

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High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells Autor Sarrafha, Lily, Parfitt, Gustavo M., Reyes, Ricardo, Goldman, Camille, Coccia, Elena, Kareva, Tatyana, Ahfeldt, Tim

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Differentiation stage determines reprogramming potential of hematopoietic cells into iPS cells Autor Eminli, Sarah, Foudi, Adlen, Stadtfeld, Matthias, Maherali, Nimet, Ahfeldt, Tim, Mostoslavsky, Gustavo, Hock, Hanno, Hochedlinger, Konrad

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Temporal Proteomics During Neurogenesis Reveals Large-scale Proteome and Organelle Remodeling via Selective Autophagy Autor Ordureau, Alban, Kraus, Felix, Zhang, Jiuchun, An, Heeseon, Park, Sookhee, Ahfeldt, Tim, Paulo, Joao A., Harper, J. Wade

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Disease-specific induced pluripotent stem (iPS) cells Autor Park, In-Hyun, Arora, Natasha, Huo, Hongguang, Maherali, Nimet, Ahfeldt, Tim, Shimamura, Akiko, Lensch, M. William, Cowan, Chad, Hochedlinger, Konrad, Daley, George Q.

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Efficient Culturing and Genetic Manipulation of Human Pluripotent Stem Cells Autor Schinzel, Robert T., Ahfeldt, Tim, Lau, Frank H., Lee, Youn-Kyoung, Cowley, Alicia, Shen, Tony, Peters, Derek, Lum, David H., Cowan, Chad A.

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Pattern Specification and Immune Response Transcriptional Signatures of Pericardial and Subcutaneous Adipose Tissue Autor Lau, Frank H., Deo, Rahul C., Mowrer, Gregory, Caplin, Joshua, Ahfeldt, Tim, Kaplan, Adam, Ptaszek, Leon, Walker, Jennifer D., Rosengard, Bruce R., Cowan, Chad A.

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Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs Autor Mou, Hongmei, Zhao, Rui, Sherwood, Richard, Ahfeldt, Tim, Lapey, Allen, Wain, John, Sicilian, Leonard, Izvolsky, Konstantin, Lau, Frank H., Musunuru, Kiran, Cowan, Chad, Rajagopal, Jayaraj

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Dynamics of PARKIN-dependent mitochondrial ubiquitylation in induced-neurons and model systems revealed by digital snapshot proteomics Autor Ordureau, Alban, Paulo, Joao A., Zhang, Wei, Ahfeldt, Tim, Zhang, Jiuchun, Cohn, Erin F., Hou, Zhonggang, Heo, Jin-Mi, Rubin, Lee L., Sidhu, Sachdev S., Gygi, Steven P., Harper, J. Wade

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Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons Autor Ahfeldt, Tim, Ordureau, Alban, Bell, Christina, Sarrafha, Lily, Sun, Chicheng, Piccinotti, Silvia, Grass, Tobias, Parfitt, Gustavo M., Paulo, Joao A., Yanagawa, Fumiki, Uozumi, Takayuki, Kiyota, Yasujiro, Harper, J. Wade, Rubin, Lee L.

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells using synthetic modified mRNA Autor Warren, Luigi, Manos, Philip D., Ahfeldt, Tim, Loh, Yuin-Han, Li, Hu, Lau, Frank, Ebina, Wataru, Mandal, Pankaj, Smith, Zachary D., Meissner, Alexander, Daley, George Q., Brack, Andrew S., Collins, James J., Cowan, Chad, Schlaeger, Thorsten M., Rossi, Derrick J.

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Programming human pluripotent stem cells into white and brown adipocytes Autor Ahfeldt, Tim, Schinzel, Robert T., Lee, Youn-Kyoung, Hendrickson, David, Kaplan, Adam, Lum, David H., Camahort, Raymond, Xia, Fang, Shay, Jennifer, Rhee, Eugene P., Clish, Clary B., Deo, Rahul C., Shen, Tony, Lau, Frank H., Cowley, Alicia, Mowrer, Greg, Al-Siddiqi, Heba, Nahrendorf, Matthias, Musunuru, Kiran, Gerszten, Robert E., Rinn, John L., Cowan, Chad A.

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Characterization of Bipolar Disorder Patient-Specific Induced Pluripotent Stem Cells from a Family Reveals Neurodevelopmental and mRNA Expression Abnormalities Autor Madison, Jon M., Zhou, Fen, Nigam, Aparna, Hussain, Ali, Barker, Douglas D., Nehme, Ralda, van der Ven, Karlijn, Hsu, Jenny, Wolf, Pavlina, Fleishman, Morgan, O’Dushlaine, Colm, Rose, Sam, Chambert, Kimberly, Lau, Frank H., Ahfeldt, Tim, Rueckert, Erroll H., Sheridan, Steven D., Fass, Daniel M., Nemesh, James, Mullen, Thomas E., Daheron, Laurence, McCarroll, Steve, Sklar, Pamela, Perlis, Roy H., Haggarty, Stephen J.

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A TALEN genome editing system to generate human stem cell-based disease models Autor Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A. K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, Marta, Gupta, Rajat M., Moisan, Annie, Banks, Eric, Friesen, Max, Schinzel, Robert T., Xia, Fang, Tang, Alexander, Xia, Yulei, Figueroa, Emmanuel, Wann, Amy, Ahfeldt, Tim, Daheron, Laurence, Zhang, Feng, Rubin, Lee L., Peng, Lee F., Chung, Raymond T., Musunuru, Kiran, Cowan, Chad A.

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus Autor Musunuru, Kiran, Strong, Alanna, Frank-Kamenetsky, Maria, Lee, Noemi E., Ahfeldt, Tim, Sachs, Katherine V., Li, Xiaoyu, Li, Hui, Kuperwasser, Nicolas, Ruda, Vera M., Pirruccello, James J., Muchmore, Brian, Prokunina-Olsson, Ludmila, Hall, Jennifer L., Schadt, Eric E., Morales, Carlos R., Lund-Katz, Sissel, Phillips, Michael C., Wong, Jamie, Cantley, William, Racie, Timothy, Ejebe, Kenechi G., Orho-Melander, Marju, Melander, Olle, Koteliansky, Victor, Fitzgerald, Kevin, Krauss, Ronald M., Cowan, Chad A., Kathiresan, Sekar, Rader, Daniel J.

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Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells Autor Navarro, Elisa, Udine, Evan, de Paiva Lopes, Katia, Parks, Madison, Riboldi, Giulietta, Schilder, Brian M., Humphrey, Jack, Snijders, Gijsje J. L., Vialle, Ricardo A., Zhuang, Maojuan, Sikder, Tamjeed, Argyrou, Charalambos, Allan, Amanda, Chao, Michael J., Farrell, Kurt, Henderson, Brooklyn, Simon, Sarah, Raymond, Deborah, Elango, Sonya, Ortega, Roberto A., Shanker, Vicki, Swan, Matthew, Zhu, Carolyn W., Ramdhani, Ritesh, Walker, Ruth H., Tse, Winona, Sano, Mary, Pereira, Ana C., Ahfeldt, Tim, Goate, Alison M., Bressman, Susan, Crary, John F., de Witte, Lotje, Frucht, Steven, Saunders-Pullman, Rachel, Raj, Towfique

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