Rezultati pretrage - Ahfeldt, Tim

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease od Coccia, Elena, Ahfeldt, Tim

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Drug discovery using neurons derived from patients: Studying Human Disease Using Human Neurons od Ahfeldt, Tim, Litterman, Nadia K., Rubin, Lee L.

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Modeling the complex genetic architectures of brain disease. od Fernando, Michael B., Ahfeldt, Tim, Brennand, Kristen J.

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Induced pluripotent stem (iPS) cells: an up-to-the-minute review od Lau, Frank, Ahfeldt, Tim, Osafune, Kenji, Akustsu, Hidenori, Cowan, Chad A

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A high efficiency system for the generation and study of human induced pluripotent stem cells od Maherali, Nimet, Ahfeldt, Tim, Rigamonti, Alessandra, Utikal, Jochen, Cowan, Chad, Hochedlinger, Konrad

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High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells od Sarrafha, Lily, Parfitt, Gustavo M., Reyes, Ricardo, Goldman, Camille, Coccia, Elena, Kareva, Tatyana, Ahfeldt, Tim

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Differentiation stage determines reprogramming potential of hematopoietic cells into iPS cells od Eminli, Sarah, Foudi, Adlen, Stadtfeld, Matthias, Maherali, Nimet, Ahfeldt, Tim, Mostoslavsky, Gustavo, Hock, Hanno, Hochedlinger, Konrad

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Temporal Proteomics During Neurogenesis Reveals Large-scale Proteome and Organelle Remodeling via Selective Autophagy od Ordureau, Alban, Kraus, Felix, Zhang, Jiuchun, An, Heeseon, Park, Sookhee, Ahfeldt, Tim, Paulo, Joao A., Harper, J. Wade

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Disease-specific induced pluripotent stem (iPS) cells od Park, In-Hyun, Arora, Natasha, Huo, Hongguang, Maherali, Nimet, Ahfeldt, Tim, Shimamura, Akiko, Lensch, M. William, Cowan, Chad, Hochedlinger, Konrad, Daley, George Q.

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Efficient Culturing and Genetic Manipulation of Human Pluripotent Stem Cells od Schinzel, Robert T., Ahfeldt, Tim, Lau, Frank H., Lee, Youn-Kyoung, Cowley, Alicia, Shen, Tony, Peters, Derek, Lum, David H., Cowan, Chad A.

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Pattern Specification and Immune Response Transcriptional Signatures of Pericardial and Subcutaneous Adipose Tissue od Lau, Frank H., Deo, Rahul C., Mowrer, Gregory, Caplin, Joshua, Ahfeldt, Tim, Kaplan, Adam, Ptaszek, Leon, Walker, Jennifer D., Rosengard, Bruce R., Cowan, Chad A.

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Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs od Mou, Hongmei, Zhao, Rui, Sherwood, Richard, Ahfeldt, Tim, Lapey, Allen, Wain, John, Sicilian, Leonard, Izvolsky, Konstantin, Lau, Frank H., Musunuru, Kiran, Cowan, Chad, Rajagopal, Jayaraj

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Dynamics of PARKIN-dependent mitochondrial ubiquitylation in induced-neurons and model systems revealed by digital snapshot proteomics od Ordureau, Alban, Paulo, Joao A., Zhang, Wei, Ahfeldt, Tim, Zhang, Jiuchun, Cohn, Erin F., Hou, Zhonggang, Heo, Jin-Mi, Rubin, Lee L., Sidhu, Sachdev S., Gygi, Steven P., Harper, J. Wade

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Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons od Ahfeldt, Tim, Ordureau, Alban, Bell, Christina, Sarrafha, Lily, Sun, Chicheng, Piccinotti, Silvia, Grass, Tobias, Parfitt, Gustavo M., Paulo, Joao A., Yanagawa, Fumiki, Uozumi, Takayuki, Kiyota, Yasujiro, Harper, J. Wade, Rubin, Lee L.

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells using synthetic modified mRNA od Warren, Luigi, Manos, Philip D., Ahfeldt, Tim, Loh, Yuin-Han, Li, Hu, Lau, Frank, Ebina, Wataru, Mandal, Pankaj, Smith, Zachary D., Meissner, Alexander, Daley, George Q., Brack, Andrew S., Collins, James J., Cowan, Chad, Schlaeger, Thorsten M., Rossi, Derrick J.

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Programming human pluripotent stem cells into white and brown adipocytes od Ahfeldt, Tim, Schinzel, Robert T., Lee, Youn-Kyoung, Hendrickson, David, Kaplan, Adam, Lum, David H., Camahort, Raymond, Xia, Fang, Shay, Jennifer, Rhee, Eugene P., Clish, Clary B., Deo, Rahul C., Shen, Tony, Lau, Frank H., Cowley, Alicia, Mowrer, Greg, Al-Siddiqi, Heba, Nahrendorf, Matthias, Musunuru, Kiran, Gerszten, Robert E., Rinn, John L., Cowan, Chad A.

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Characterization of Bipolar Disorder Patient-Specific Induced Pluripotent Stem Cells from a Family Reveals Neurodevelopmental and mRNA Expression Abnormalities od Madison, Jon M., Zhou, Fen, Nigam, Aparna, Hussain, Ali, Barker, Douglas D., Nehme, Ralda, van der Ven, Karlijn, Hsu, Jenny, Wolf, Pavlina, Fleishman, Morgan, O’Dushlaine, Colm, Rose, Sam, Chambert, Kimberly, Lau, Frank H., Ahfeldt, Tim, Rueckert, Erroll H., Sheridan, Steven D., Fass, Daniel M., Nemesh, James, Mullen, Thomas E., Daheron, Laurence, McCarroll, Steve, Sklar, Pamela, Perlis, Roy H., Haggarty, Stephen J.

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A TALEN genome editing system to generate human stem cell-based disease models od Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A. K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, Marta, Gupta, Rajat M., Moisan, Annie, Banks, Eric, Friesen, Max, Schinzel, Robert T., Xia, Fang, Tang, Alexander, Xia, Yulei, Figueroa, Emmanuel, Wann, Amy, Ahfeldt, Tim, Daheron, Laurence, Zhang, Feng, Rubin, Lee L., Peng, Lee F., Chung, Raymond T., Musunuru, Kiran, Cowan, Chad A.

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus od Musunuru, Kiran, Strong, Alanna, Frank-Kamenetsky, Maria, Lee, Noemi E., Ahfeldt, Tim, Sachs, Katherine V., Li, Xiaoyu, Li, Hui, Kuperwasser, Nicolas, Ruda, Vera M., Pirruccello, James J., Muchmore, Brian, Prokunina-Olsson, Ludmila, Hall, Jennifer L., Schadt, Eric E., Morales, Carlos R., Lund-Katz, Sissel, Phillips, Michael C., Wong, Jamie, Cantley, William, Racie, Timothy, Ejebe, Kenechi G., Orho-Melander, Marju, Melander, Olle, Koteliansky, Victor, Fitzgerald, Kevin, Krauss, Ronald M., Cowan, Chad A., Kathiresan, Sekar, Rader, Daniel J.

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Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells od Navarro, Elisa, Udine, Evan, de Paiva Lopes, Katia, Parks, Madison, Riboldi, Giulietta, Schilder, Brian M., Humphrey, Jack, Snijders, Gijsje J. L., Vialle, Ricardo A., Zhuang, Maojuan, Sikder, Tamjeed, Argyrou, Charalambos, Allan, Amanda, Chao, Michael J., Farrell, Kurt, Henderson, Brooklyn, Simon, Sarah, Raymond, Deborah, Elango, Sonya, Ortega, Roberto A., Shanker, Vicki, Swan, Matthew, Zhu, Carolyn W., Ramdhani, Ritesh, Walker, Ruth H., Tse, Winona, Sano, Mary, Pereira, Ana C., Ahfeldt, Tim, Goate, Alison M., Bressman, Susan, Crary, John F., de Witte, Lotje, Frucht, Steven, Saunders-Pullman, Rachel, Raj, Towfique

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