Søgeresultater - Afshan McCarthy

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  1. 1
    <i>Lkb1</i> Deficiency Causes Prostate Neoplasia in the Mouse

    <i>Lkb1</i> Deficiency Causes Prostate Neoplasia in the Mouse af Helen Pearson, Afshan McCarthy, Christopher M. Collins, Alan Ashworth, Alan R. Clarke

    Udgivet 2008
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  2. 2
    A targeted deletion in the endocytic receptor gene <i>Endo180</i> results in a defect in collagen uptake

    A targeted deletion in the endocytic receptor gene <i>Endo180</i> results in a defect in collagen uptake af Lucy East, Afshan McCarthy, Dirk Wienke, Justin Sturge, Alan Ashworth, Clare M. Isacke

    Udgivet 2003
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  3. 3
    Aurora‐A expressing tumour cells are deficient for homology‐directed DNA double strand‐break repair and sensitive to PARP inhibition

    Aurora‐A expressing tumour cells are deficient for homology‐directed DNA double strand‐break repair and sensitive to PARP inhibition af Tony Sourisseau, Despina Maniotis, Afshan McCarthy, Chan Tang, Christopher J. Lord, Alan Ashworth, Spiros Linardopoulos

    Udgivet 2010
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  4. 4
    Genetic Deletion of RALA and RALB Small GTPases Reveals Redundant Functions in Development and Tumorigenesis

    Genetic Deletion of RALA and RALB Small GTPases Reveals Redundant Functions in Development and Tumorigenesis af Pascal Peschard, Afshan McCarthy, Valérie Leblanc-Dominguez, Maggie Yeo, Sabrina Guichard, Gordon Stamp, Christopher J. Marshall

    Udgivet 2012
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  5. 5
    Chromosomal localization of human genes for arylamine <i>N</i>-acetyltransferase

    Chromosomal localization of human genes for arylamine <i>N</i>-acetyltransferase af Dean Hickman, Angela Risch, V J Buckle, N.K. Spurr, S.J. Jeremiah, Afshan McCarthy, Edith Sim

    Udgivet 1994
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  6. 6
    Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene <i>MSH2</i>

    Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene <i>MSH2</i> af Sarah A. Martin, Afshan McCarthy, Louise J. Barber, Darren J. Burgess, Suzanne Parry, Christopher J. Lord, Alan Ashworth

    Udgivet 2009
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  7. 7
    Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

    Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction af Kei Sakamoto, Afshan McCarthy, Darrin P. Smith, Kevin A. Green, D. Grahame Hardie, Alan Ashworth, Dario R. Alessi

    Udgivet 2005
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  8. 8
    Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions

    Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions af Faraz K. Mardakheh, Angela Paul, Sandra Kümper, Amine Sadok, Hugh Paterson, Afshan McCarthy, Yinyin Yuan, Christopher J. Marshall

    Udgivet 2015
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  9. 9
    Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

    Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine af Boris Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen Pearson, Douglas J. Winton, Owen J. Sansom, Alan Ashworth, Alan R. Clarke

    Udgivet 2009
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  10. 10
    Tumor suppressor role of phospholipase Cε in Ras-triggered cancers

    Tumor suppressor role of phospholipase Cε in Ras-triggered cancers af Marta Martins, Afshan McCarthy, Rhona W. Baxendale, Sabrina Guichard, Lorenza Magno, Nicoletta Kessaris, Mona El‐Bahrawy, Philipp Yu, Matilda Katan

    Udgivet 2014
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  11. 11
    MICA: a multi-omics method to predict gene regulatory networks in early human embryos

    MICA: a multi-omics method to predict gene regulatory networks in early human embryos af Gregorio Alanis‐Lobato, Thomas E. Bartlett, Qiulin Huang, Claire Simon, Afshan McCarthy, Kay Elder, Phil Snell, Leila Christie, Kathy K. Niakan

    Udgivet 2023
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  12. 12
    Aurora A Kinase Regulates Mammary Epithelial Cell Fate by Determining Mitotic Spindle Orientation in a Notch-Dependent Manner

    Aurora A Kinase Regulates Mammary Epithelial Cell Fate by Determining Mitotic Spindle Orientation in a Notch-Dependent Manner af Joseph L. Regan, Tony Sourisseau, Kelly Soady, Howard Kendrick, Afshan McCarthy, Chan Tang, Keith Brennan, Spiros Linardopoulos, Donald White, Matthew J. Smalley

    Udgivet 2013
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  13. 13
    Synthetic lethal targeting of <i>PTEN</i> mutant cells with PARP inhibitors

    Synthetic lethal targeting of <i>PTEN</i> mutant cells with PARP inhibitors af Ana M. Mendes‐Pereira, Sarah A. Martin, Rachel Brough, Afshan McCarthy, J R Taylor, Jung‐Sik Kim, Todd Waldman, Christopher J. Lord, Alan Ashworth

    Udgivet 2009
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  14. 14
    Rho Kinase Inhibitors Block Melanoma Cell Migration and Inhibit Metastasis

    Rho Kinase Inhibitors Block Melanoma Cell Migration and Inhibit Metastasis af Amine Sadok, Afshan McCarthy, John Caldwell, Ian Collins, Michelle D. Garrett, Maggie Yeo, Steven Hooper, Erik Sahai, Sandra Kuemper, Faraz K. Mardakheh, Christopher J. Marshall

    Udgivet 2015
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  15. 15
    Frequent loss of heterozygosity in CRISPR-Cas9–edited early human embryos

    Frequent loss of heterozygosity in CRISPR-Cas9–edited early human embryos af Gregorio Alanis‐Lobato, Jasmin Zohren, Afshan McCarthy, Norah M. E. Fogarty, Nada Kubikova, Emily Hardman, Maria Greco, Dagan Wells, James M. A. Turner, Kathy K. Niakan

    Udgivet 2021
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  16. 16
    BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

    BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells af Gemma Molyneux, Felipe C. Geyer, Fiona‐Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan Mackay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis‐Filho, Matthew J. Smalley

    Udgivet 2010
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  17. 17
    A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer

    A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer af Monika Graeser, Afshan McCarthy, Christopher J. Lord, Kay Savage, Margaret Hills, Janine Salter, Nick Orr, Marina Parton, Ian E. Smith, Jorge S. Reis‐Filho, Mitch Dowsett, Alan Ashworth, Nicholas C. Turner

    Udgivet 2010
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  18. 18
    A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

    A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes af Zheng Yin, Amine Sadok, Heba Sailem, Afshan McCarthy, Xiaofeng Xia, Fuhai Li, Mar Arias-García, Louise Evans, Alexis R. Barr, Norbert Perrimon, Christopher J. Marshall, Stephen T.C. Wong, Chris Bakal

    Udgivet 2013
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  19. 19
    TRF2-independent chromosome end protection during pluripotency

    TRF2-independent chromosome end protection during pluripotency af Phil Ruis, David Ly, Valérie Borel, Georgia R. Kafer, Afshan McCarthy, Steven Howell, Robert Blassberg, Ambrosius P. Snijders, James Briscoe, Kathy K. Niakan, Paulina Marzec, Anthony J. Cesare, Simon J. Boulton

    Udgivet 2020
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  20. 20
    <scp>AGE</scp> ‐modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival

    <scp>AGE</scp> ‐modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival af Mercedes Rodríguez, Julian H. Gronau, Claudia Breit, Yu Zhi Zhang, Ai Minamidate, Matthew Caley, Afshan McCarthy, Thomas R. Cox, Janine T. Erler, Luke Gaughan, Steven Darby, Craig Robson, Francesco Mauri, Jonathan Waxman, Justin Sturge

    Udgivet 2014
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