Resultados da pesquisa - Adrian M. Dubuc

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  1. 1
    The current state of clinical interpretation of sequence variants

    The current state of clinical interpretation of sequence variants Por Derick Hoskinson, Adrian M. Dubuc, Heather Mason‐Suares

    Publicado em 2017
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  2. 2
    Molecular subgroups of medulloblastoma

    Molecular subgroups of medulloblastoma Por Paul A. Northcott, Adrian M. Dubuc, Stefan M. Pfister, Michael D. Taylor

    Publicado em 2012
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  3. 3
    Targeting the enhancer of zeste homologue 2 in medulloblastoma

    Targeting the enhancer of zeste homologue 2 in medulloblastoma Por Irina Alimova, Sujatha Venkataraman, Peter S. Harris, Víctor E. Márquez, Paul A. Northcott, Adrian M. Dubuc, Michael D. Taylor, Nicholas K. Foreman, Rajeev Vibhakar

    Publicado em 2012
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  4. 4
    Technical laboratory standards for interpretation and reporting of acquired copy-number abnormalities and copy-neutral loss of heterozygosity in neoplastic disorders: a joint consensus recommendation from the American College of Medical Genetics and Genomics (ACMG) and the Cancer Genomics Consortium (CGC)

    Technical laboratory standards for interpretation and reporting of acquired copy-number abnormalities and copy-neutral loss of heterozygosity in neoplastic disorders: a joint conse... Por Fady M. Mikhail, Jaclyn A. Biegel, Linda D. Cooley, Adrian M. Dubuc, Betsy Hirsch, Vanessa L. Horner, Scott Newman, Lina Shao, Daynna J. Wolff, Gordana Raca

    Publicado em 2019
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  5. 5
    Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma

    Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma Por Giulio Fiaschetti, Lucia Abela, Naosuke Nonoguchi, Adrian M. Dubuc, Marc Remke, Aleksandar Boro, Eveline Grunder, Ulrich Siler, Hideaki Ohgaki, Michael D. Taylor, Martin Baumgartner, T. Shalaby, Michael Grotzer

    Publicado em 2013
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  6. 6
    MicroRNA 218 Acts as a Tumor Suppressor by Targeting Multiple Cancer Phenotype-associated Genes in Medulloblastoma

    MicroRNA 218 Acts as a Tumor Suppressor by Targeting Multiple Cancer Phenotype-associated Genes in Medulloblastoma Por Sujatha Venkataraman, Diane K. Birks, Ilango Balakrishnan, Irina Alimova, Peter S. Harris, Purvi Patel, Michael H. Handler, Adrian M. Dubuc, Michael D. Taylor, Nicholas K. Foreman, Rajeev Vibhakar

    Publicado em 2012
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  7. 7
    Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

    Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells Por Peter S. Harris, Sujatha Venkataraman, Irina Alimova, Diane K. Birks, Andrew M. Donson, Jeffrey Knipstein, Adrian M. Dubuc, Michael D. Taylor, Michael H. Handler, Nicholas K. Foreman, Rajeev Vibhakar

    Publicado em 2012
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  8. 8
    Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma

    Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma Por Peter S. Harris, Sujatha Venkataraman, Irina Alimova, Diane K. Birks, Ilango Balakrishnan, Brian Cristiano, Andrew M. Donson, Adrian M. Dubuc, Michael D. Taylor, Nicholas K. Foreman, Philip Reigan, Rajeev Vibhakar

    Publicado em 2014
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  9. 9
    CXCR4 Activation Defines a New Subgroup of Sonic Hedgehog–Driven Medulloblastoma

    CXCR4 Activation Defines a New Subgroup of Sonic Hedgehog–Driven Medulloblastoma Por Rajarshi Sengupta, Adrian M. Dubuc, Stacey Ward, Lihua Yang, Paul A. Northcott, B. Mark Woerner, Kristen L. Kroll, Jingqin Luo, Michael D. Taylor, Robert J. Wechsler‐Reya, Joshua B. Rubin

    Publicado em 2011
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  10. 10
    Quantification of aneuploidy in targeted sequencing data using ASCETS

    Quantification of aneuploidy in targeted sequencing data using ASCETS Por Liam F. Spurr, Mehdi Touat, Alison M. Taylor, Adrian M. Dubuc, Juliann Shih, David M. Meredith, William Pisano, Matthew Meyerson, Keith L. Ligon, Andrew D. Cherniack, Yvonne Y. Li, Rameen Beroukhim

    Publicado em 2020
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  11. 11
    Yield of additional genetic testing after chromosomal microarray for diagnosis of neurodevelopmental disability and congenital anomalies: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)

    Yield of additional genetic testing after chromosomal microarray for diagnosis of neurodevelopmental disability and congenital anomalies: a clinical practice resource of the Americ... Por Darrel Waggoner, Karen E. Wain, Adrian M. Dubuc, Laura K. Conlin, Scott E. Hickey, Allen N. Lamb, Christa Lese Martin, Cynthia C. Morton, Kristen Rasmussen, Jane L. Schuette, Stuart Schwartz, David T. Miller

    Publicado em 2018
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  12. 12
    Guiding the global evolution of cytogenetic testing for hematologic malignancies

    Guiding the global evolution of cytogenetic testing for hematologic malignancies Por Yassmine Akkari, Linda B. Baughn, Adrian M. Dubuc, Adam C. Smith, Mar Mallo, Paola Dal Cin, María Díez‐Campelo, Marta S. Gallego, Isabel Granada, D. Haase, Brigitte Schlegelberger, Irma Slavutsky, Cristina Mecucci, Ross L. Levine, Robert P. Hasserjian, Françesc Solé, Brynn Levy, Xinjie Xu

    Publicado em 2022
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  13. 13
    Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

    Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples Por Paul A. Northcott, David Shih, Marc Remke, Yoon‐Jae Cho, Marcel Kool, Cynthia Hawkins, Charles G. Eberhart, Adrian M. Dubuc, Toumy Guettouche, Yoslayma Cardentey, Éric Bouffet, Scott L. Pomeroy, Marco A. Marra, David Malkin, James T. Rutka, Andrey Korshunov, Stefan M. Pfister, Michael D. Taylor

    Publicado em 2011
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  14. 14
    Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

    Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct Por Paul A. Northcott, Thomas Hielscher, Adrian M. Dubuc, Stephen C. Mack, David Shih, Marc Remke, H. Al-Halabi, Steffen Albrecht, Nada Jabado, Charles G. Eberhart, Wiesława Grajkowska, William A. Weiss, Steven C. Clifford, Éric Bouffet, James T. Rutka, Andrey Korshunov, Stefan M. Pfister, Michael D. Taylor

    Publicado em 2011
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  15. 15
    Mismatch Repair Deficiency in High-Grade Meningioma: A Rare but Recurrent Event Associated With Dramatic Immune Activation and Clinical Response to PD-1 Blockade

    Mismatch Repair Deficiency in High-Grade Meningioma: A Rare but Recurrent Event Associated With Dramatic Immune Activation and Clinical Response to PD-1 Blockade Por Ian F. Dunn, Ziming Du, Mehdi Touat, Michael B. Sisti, Patrick Y. Wen, Renato Umeton, Adrian M. Dubuc, Matthew D. Ducar, Peter Canoll, Eric A. Severson, Julia A. Elvin, Shakti Ramkissoon, Jia‐Ren Lin, Lais Cabrera, Brenda Acevedo, Peter K. Sorger, Keith L. Ligon, Sandro Santagata, David A. Reardon

    Publicado em 2018
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  16. 16
    Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics

    Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics Por Xi Huang, Adrian M. Dubuc, Rintaro Hashizume, Jim Berg, Ye He, Ji Wang, Chin Chiang, Michael K. Cooper, Paul A. Northcott, Michael D. Taylor, Michael J. Barnes, Tarık Tihan, Justin Chen, Christopher S. Hackett, William A. Weiss, C. David James, David H. Rowitch, Marc A. Shuman, Yuh Nung Jan, Lily Yeh Jan

    Publicado em 2012
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  17. 17
    The RNA-Binding Protein Musashi1 Affects Medulloblastoma Growth via a Network of Cancer-Related Genes and Is an Indicator of Poor Prognosis

    The RNA-Binding Protein Musashi1 Affects Medulloblastoma Growth via a Network of Cancer-Related Genes and Is an Indicator of Poor Prognosis Por Dat T. Vo, Dharmalingam Subramaniam, Marc Remke, Tarea L. Burton, Philip J. Uren, Jonathan A.L. Gelfond, Raquel de Sousa Abreu, Suzanne Burns, Mei Qiao, Uthra Suresh, Andrey Korshunov, Adrian M. Dubuc, Paul A. Northcott, Andrew D. Smith, Stefan M. Pfister, Michael D. Taylor, Sarath Chandra Janga, Shrikant Anant, Christine Vogel, Luiz O. F. Penalva

    Publicado em 2012
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  18. 18
    Integrative cytogenetic and molecular studies unmask “chromosomal mimicry” in hematologic malignancies

    Integrative cytogenetic and molecular studies unmask “chromosomal mimicry” in hematologic malignancies Por Melissa Zhao, Scott Ryall, Sam J. Brody, Amyah C. Harris, Kristin Cabral, Catherine A. Brownstein, Jaeseung Kim, Adam C. Smith, Paola Dal Cin, Rupa Narayan, Kristin Sikkink, Anthony D. Schmitt, Gabriela S. Hobbs, Amir T. Fathi, Gabriel K. Griffin, Sheila N.J. Sait, A. John Iafrate, Jon C. Aster, Timothy A. Graubert, Valentina Nardi, Adrian M. Dubuc

    Publicado em 2025
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  19. 19
    Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma

    Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Por Cláudia C. Faria, Brian Golbourn, Adrian M. Dubuc, Marc Remke, Roberto J. Diaz, Sameer Agnihotri, Amanda Luck, N. Sabha, Samantha Olsen, Xiaochong Wu, Livia Garzia, Vijay Ramaswamy, Stephen C. Mack, Xin Wang, Michael Leadley, Dénis Reynaud, Leonardo Ermini, Martin Post, Paul A. Northcott, Stefan M. Pfister, Sidney Croul, Marcel Kool, Andrey Korshunov, Christian A. Smith, Michael D. Taylor, James T. Rutka

    Publicado em 2014
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  20. 20
    Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma

    Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma Por Adrian M. Dubuc, Marc Remke, Andrey Korshunov, Paul A. Northcott, Shing H. Zhan, María Méndez-Lago, Marcel Kool, David Jones, Alexander Unterberger, A. Sorana Morrissy, David Shih, John Peacock, Vijay Ramaswamy, Adi Rolider, Xin Wang, Hendrik Witt, Thomas Hielscher, Cynthia Hawkins, Rajeev Vibhakar, Sidney Croul, James T. Rutka, William A. Weiss, Steven J.M. Jones, Charles G. Eberhart, Marco A. Marra, Stefan M. Pfister, Michael D. Taylor

    Publicado em 2012
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