Search Results - Adhirai Marimuthu

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  1. 1
    Triiodothyronine Increases Brain Natriuretic Peptide (BNP) Gene Transcription and Amplifies Endothelin-dependent BNP Gene Transcription and Hypertrophy in Neonatal Rat Ventricular Myocytes

    Triiodothyronine Increases Brain Natriuretic Peptide (BNP) Gene Transcription and Amplifies Endothelin-dependent BNP Gene Transcription and Hypertrophy in Neonatal Rat Ventricular... by Faquan Liang, Paul Webb, Adhirai Marimuthu, Sumei Zhang, David G. Gardner

    Published 2003
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  2. 2
    TR Surfaces and Conformations Required to Bind Nuclear Receptor Corepressor

    TR Surfaces and Conformations Required to Bind Nuclear Receptor Corepressor by Adhirai Marimuthu, Weijun Feng, Tetsuya Tagami, Hoa Nguyen, J. Larry Jameson, Robert J. Fletterick, John D. Baxter, Brian L. West

    Published 2002
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  3. 3
    Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase

    Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase by Weiru Wang, Adhirai Marimuthu, James Tsai, Abhinav Kumar, Heike I. Krupka, Chao Zhang, Ben Powell, Yoshihisa Suzuki, Hoa Nguyen, M. Tabrizizad, Catherine A. Luu, Brian L. West

    Published 2006
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  4. 4
    The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1

    The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1 by Weiru Wang, Chao Zhang, Adhirai Marimuthu, Heike I. Krupka, M. Tabrizizad, R. Shelloe, Upasana Mehra, Kevin H. Eng, Hoa Nguyen, Calvin Settachatgul, Ben Powell, Michael V. Milburn, Brian L. West

    Published 2005
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  5. 5
    Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

    Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors by Robert Wesolowski, Neelesh Sharma, Laura Reebel, Mary Beth Rodal, Peck Alexandra, Brian L. West, Adhirai Marimuthu, Paul Severson, David A. Karlin, Afshin Dowlati, Mai H. Le, Lisa M. Coussens, Hope S. Rugo

    Published 2019
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  6. 6
    Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

    Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study by Nicholas Butowski, Howard Colman, John de Groot, Antonio Omuro, Lakshmi Nayak, Patrick Y. Wen, Timothy F. Cloughesy, Adhirai Marimuthu, Sam Haidar, Arie Perry, Jason T. Huse, Joanna J. Phillips, Brian L. West, K. B. Nolop, Henry H. Hsu, Keith L. Ligon, Annette M. Molinaro, Michael D. Prados

    Published 2015
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  7. 7
    Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor

    Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor by Chao Zhang, Prabha N. Ibrahim, Jiazhong Zhang, Elizabeth A. Burton, Gaston Habets, Ying Zhang, Ben Powell, Brian L. West, Bernice Matusow, Garson Tsang, Rafe Shellooe, Heidi Carias, Hoa Nguyen, Adhirai Marimuthu, Kam Y. J. Zhang, Angela J. Oh, Ryan Bremer, Clarence R. Hurt, Dean R. Artis, Guoxian Wu, Marika Nespi, Wayne Spevak, Paul Lin, K. B. Nolop, Peter Hirth, Greg H. Tesch, Gideon Bollag

    Published 2013
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  8. 8
    Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

    Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity by James Tsai, John Tayu Lee, Weiru Wang, Jiazhong Zhang, Hanna Cho, Shumeye Mamo, Ryan Bremer, S. Gillette, Jun Kong, Nikolas K. Haass, Katrin Sproesser, Ling Li, Keiran S.M. Smalley, Daniel W. Fong, Yongliang Zhu, Adhirai Marimuthu, Hoa Nguyen, Billy Lam, Jennifer Liu, Ivana Cheung, Julie Rice, Yoshihisa Suzuki, Catherine A. Luu, Calvin Settachatgul, Rafe Shellooe, John Cantwell, Sung‐Hou Kim, Joseph Schlessinger, Kam Y. J. Zhang, Brian L. West, Ben Powell, Gaston Habets, Chao Zhang, Prabha N. Ibrahim, Peter Hirth, Dean R. Artis, Meenhard Herlyn, Gideon Bollag

    Published 2008
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  9. 9
    Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

    Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent by Dean R. Artis, Jack J. Lin, Chao Zhang, Weiru Wang, Upasana Mehra, Mylène Perreault, David V. Erbe, Heike I. Krupka, B.P. England, J. Malcolm O. Arnold, A.N. Plotnikov, Adhirai Marimuthu, Hoa Nguyen, Sarah Will, Maxime Signaevsky, John G. Kral, John Cantwell, Calvin Settachatgull, Douglas S. Yan, Daniel W. Fong, Angela J. Oh, Shenghua Shi, Patrick Womack, Benjamin E. Powell, Gaston Habets, Brian L. West, Kam Y. J. Zhang, Michael V. Milburn, George P. Vlasuk, K. Peter Hirth, K. B. Nolop, Gideon Bollag, Prabha N. Ibrahim, James F. Tobin

    Published 2008
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  10. 10
    Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

    Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma by Gideon Bollag, Peter Hirth, James Tsai, Jiazhong Zhang, Prabha N. Ibrahim, Hanna Cho, Wayne Spevak, Chao Zhang, Ying Zhang, Gaston Habets, Elizabeth A. Burton, Bernice H. Wong, Garson Tsang, Brian L. West, Ben Powell, Rafe Shellooe, Adhirai Marimuthu, Hoa Nguyen, Kam Y. J. Zhang, Dean R. Artis, Joseph Schlessinger, Fei Su, Brian Higgins, Raman Iyer, Kurt D’Andrea, Astrid Koehler, Michael Stumm, Paul Lin, Richard J. Lee, Joseph F. Grippo, Igor Puzanov, Kevin B. Kim, Antoni Ribas, Grant A. McArthur, Jeffrey A. Sosman, Paul B. Chapman, Keith T. Flaherty, Xiaowei Xu, Katherine L. Nathanson, K. B. Nolop

    Published 2010
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  11. 11
    BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor

    BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor by Hatice Gülçin Özer, Dalia El‐Gamal, Ben Powell, Zachary A. Hing, James S. Blachly, Bonnie K. Harrington, Shaneice Mitchell, Nicole R. Grieselhuber, Katie Williams, Tzung-Huei Lai, Lapo Alinari, Robert A. Baiocchi, Lindsey T. Brinton, Elizabeth Baskin, Matthew Cannon, Larry Beaver, Virginia M. Goettl, David Lucas, Jennifer A. Woyach, Deepa Sampath, Amy M. Lehman, Lianbo Yu, Jiazhong Zhang, Yan Ma, Ying Zhang, Wayne Spevak, Songyuan Shi, Paul Severson, Rafe Shellooe, Heidi Carias, Garson Tsang, Ken C. Dong, Todd Ewing, Adhirai Marimuthu, Christina Tantoy, Jason Walters, Laura Sanftner, Hamid Rezaei, Marika Nespi, Bernice Matusow, Gaston Habets, Prabha N. Ibrahim, Chao Zhang, Ewy A. Mathé, Gideon Bollag, John C. Byrd, Rosa Lapalombella

    Published 2018
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  12. 12
    Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

    Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor by William D. Tap, Zev A. Wainberg, Stephen P. Anthony, Prabha N. Ibrahim, Chao Zhang, John H. Healey, Bartosz Chmielowski, Arthur P. Staddon, Allen Lee Cohn, Geoffrey I. Shapiro, Vicki L. Keedy, Arun S. Singh, Igor Puzanov, Eunice L. Kwak, Andrew J. Wagner, Daniel D. Von Hoff, Glen J. Weiss, Ramesh K. Ramanathan, Jiazhong Zhang, Gaston Habets, Ying Zhang, Elizabeth A. Burton, Gary C. Visor, Laura Sanftner, Paul Severson, Hoa Nguyen, Marie J. Kim, Adhirai Marimuthu, Garson Tsang, Rafe Shellooe, C. M. Gee, Brian L. West, Peter Hirth, K. B. Nolop, Matt van de Rijn, Henry H. Hsu, Charles Peterfy, Paul Lin, Sandra Tong-Starksen, Gideon Bollag

    Published 2015
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