Výsledky vyhledávání - Aaron McKenna

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  1. 1
    FlashFry: a fast and flexible tool for large-scale CRISPR target design

    FlashFry: a fast and flexible tool for large-scale CRISPR target design Autor Aaron McKenna, Jay Shendure

    Vydáno 2018
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  2. 2
    Recording development with single cell dynamic lineage tracing

    Recording development with single cell dynamic lineage tracing Autor Aaron McKenna, James A. Gagnon

    Vydáno 2019
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  3. 3
    ContEst: estimating cross-contamination of human samples in next-generation sequencing data

    ContEst: estimating cross-contamination of human samples in next-generation sequencing data Autor Kristian Cibulskis, Aaron McKenna, Tim Fennell, Eric Banks, Mark A. DePristo, Gad Getz

    Vydáno 2011
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  4. 4
    Whole-organism lineage tracing by combinatorial and cumulative genome editing

    Whole-organism lineage tracing by combinatorial and cumulative genome editing Autor Aaron McKenna, Gregory M. Findlay, James A. Gagnon, Marshall S. Horwitz, Alexander F. Schier, Jay Shendure

    Vydáno 2016
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  5. 5
    Massively parallel profiling and predictive modeling of the outcomes of CRISPR/Cas9-mediated double-strand break repair

    Massively parallel profiling and predictive modeling of the outcomes of CRISPR/Cas9-mediated double-strand break repair Autor Wei Chen, Aaron McKenna, Jacob Schreiber, Maximilian Haeussler, Yi Yin, Vikram Agarwal, William Stafford Noble, Jay Shendure

    Vydáno 2019
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  6. 6
    CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions

    CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions Autor Molly Gasperini, Gregory M. Findlay, Aaron McKenna, Jennifer H. Milbank, Choli Lee, Melissa D. Zhang, Darren A. Cusanovich, Jay Shendure

    Vydáno 2017
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  7. 7
    Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain

    Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain Autor Bushra Raj, Daniel E. Wagner, Aaron McKenna, Shristi Pandey, Allon M. Klein, Jay Shendure, James A. Gagnon, Alexander F. Schier

    Vydáno 2018
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  8. 8
    Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

    Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci Autor Qiyuan Li, Ji-Heui Seo, Barbara E. Stranger, Aaron McKenna, Itsik Pe’er, Thomas LaFramboise, Myles Brown, Svitlana Tyekucheva, Matthew L. Freedman

    Vydáno 2013
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  9. 9
    Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states

    Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states Autor Kamen P. Simeonov, China N. Byrns, Megan L. Clark, Robert J. Norgard, Beth Martin, Ben Z. Stanger, Jay Shendure, Aaron McKenna, Christopher J. Lengner

    Vydáno 2021
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  10. 10
    Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

    Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors Autor Juliann Chmielecki, Aimeé M. Crago, Mara Rosenberg, Rachael O’Connor, Sarah R. Walker, Lauren Ambrogio, Daniel Auclair, Aaron McKenna, Michael C. Heinrich, David A. Frank, Matthew Meyerson

    Vydáno 2013
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  11. 11
    Emergence of Neuronal Diversity during Vertebrate Brain Development

    Emergence of Neuronal Diversity during Vertebrate Brain Development Autor Bushra Raj, Jeffrey A. Farrell, Jialin Liu, Jakob El Kholtei, Adam N. Carte, Joaquín Navajas Acedo, Lucia Y. Du, Aaron McKenna, Đorđe Relić, Jessica M. Leslie, Alexander F. Schier

    Vydáno 2020
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  12. 12
    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice Autor Chris M. Brewer, Branden R. Nelson, Paul Wakenight, Sarah Collins, Daryl M. Okamura, Xiu Rong Dong, William M. Mahoney, Aaron McKenna, Jay Shendure, Andrew E. Timms, Kathleen J. Millen, Mark W. Majesky

    Vydáno 2021
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  13. 13
    Absolute quantification of somatic DNA alterations in human cancer

    Absolute quantification of somatic DNA alterations in human cancer Autor Scott L. Carter, Kristian Cibulskis, Elena Helman, Aaron McKenna, Hui Shen, Travis Zack, Peter W. Laird, Robert C. Onofrio, Wendy Winckler, Barbara A. Weir, Rameen Beroukhim, David Pellman, Douglas A. Levine, Eric S. Lander, Matthew Meyerson, Gad Getz

    Vydáno 2012
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  14. 14
    A framework for variation discovery and genotyping using next-generation DNA sequencing data

    A framework for variation discovery and genotyping using next-generation DNA sequencing data Autor Mark A. DePristo, Eric Banks, Ryan Poplin, Kiran Garimella, Jared Maguire, Christopher Hartl, Anthony Philippakis, Guillermo del Angel, Manuel A. Rivas, Matt Hanna, Aaron McKenna, Tim Fennell, Andrew Kernytsky, Andrey Sivachenko, Kristian Cibulskis, Stacey Gabriel, David Altshuler, Mark J. Daly

    Vydáno 2011
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  15. 15
    A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

    A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival Autor Siyuan Zheng, Jun Fu, Rahulsimham Vegesna, Yong Mao, Lindsey Heathcock, Wandaliz Torres‐García, Ravesanker Ezhilarasan, Shuzhen Wang, Aaron McKenna, Lynda Chin, Cameron Brennan, W.K. Alfred Yung, John N. Weinstein, Kenneth Aldape, Erik P. Sulman, Ken Chen, Dimpy Koul, Roel G.W. Verhaak

    Vydáno 2013
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  16. 16
    Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

    Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations Autor Priscilla K. Brastianos, Peleg Horowitz, Sandro Santagata, Robert T. Jones, Aaron McKenna, Gad Getz, Keith L. Ligon, Emanuele Palescandolo, Paul Van Hummelen, Matthew D. Ducar, Alina Raza, Ashwini Sunkavalli, Laura E. MacConaill, Anat Stemmer‐Rachamimov, David N. Louis, William C. Hahn, Ian F. Dunn, Rameen Beroukhim

    Vydáno 2013
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  17. 17
    Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

    Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing Autor David G. McFadden, Thales Papagiannakopoulos, Amaro Taylor‐Weiner, Chip Stewart, Scott L. Carter, Kristian Cibulskis, Arjun Bhutkar, Aaron McKenna, Alison L. Dooley, Amanda Vernon, Carrie Sougnez, Scott Malstrom, Megan Heimann, Jennifer Park, Frances S. Chen, Anna F. Farago, Talya L. Dayton, Erica Shefler, Stacey Gabriel, Gad Getz, Tyler Jacks

    Vydáno 2014
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  18. 18
    Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences

    Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences Autor Trevor J. Pugh, Yu Wang, Jian Yang, Amanda L. Field, Lauren Ambrogio, S L Carter, Kristian Cibulskis, Petros Giannikopoulos, Adam Kieżun, J Kim, Aaron McKenna, Elizabeth Nickerson, Gad Getz, S Hoffher, Yoav H. Messinger, Louis P. Dehner, Charles W.M. Roberts, Carlos Rodríguez‐Galindo, Gretchen M. Williams, Christopher Rossi, Matthew Meyerson, D. Ashley Hill

    Vydáno 2014
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  19. 19
    Paired exome analysis of Barrett's esophagus and adenocarcinoma

    Paired exome analysis of Barrett's esophagus and adenocarcinoma Autor Matthew D. Stachler, Amaro Taylor‐Weiner, Shouyong Peng, Aaron McKenna, Agoston T. Agoston, Robert D. Odze, Jon M. Davison, Katie S. Nason, Massimo Loda, Ignaty Leshchiner, Chip Stewart, Petar Stojanov, Sara Seepo, Michael S. Lawrence, Daysha Ferrer-Torres, Jules Lin, Andrew C. Chang, Stacey Gabriel, Eric S. Lander, David G. Beer, Gad Getz, Scott L. Carter, Adam J. Bass

    Vydáno 2015
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  20. 20
    Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

    Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia Autor Dan A. Landau, Scott L. Carter, Petar Stojanov, Aaron McKenna, Kristen E. Stevenson, Michael S. Lawrence, Carrie Sougnez, Chip Stewart, Andrey Sivachenko, Lili Wang, Youzhong Wan, Wandi Zhang, Sachet A. Shukla, Alexander R. Vartanov, Stacey M. Fernandes, Gordon Saksena, Kristian Cibulskis, Bethany Tesar, Stacey Gabriel, Nir Hacohen, Matthew Meyerson, Eric S. Lander, Donna Neuberg, Jennifer R. Brown, Gad Getz, Catherine J. Wu

    Vydáno 2013
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