Suchergebnisse - A. Craig Lockhart

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  1. 1
    Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy

    Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy von Nilay Thakkar, A. Craig Lockhart, Wooin Lee

    Veröffentlicht 2015
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  2. 2
    Immune checkpoints and immunotherapy for colorectal cancer

    Immune checkpoints and immunotherapy for colorectal cancer von Preet Paul Singh, Piyush Kumar Sharma, Gayathri Krishnan, A. Craig Lockhart

    Veröffentlicht 2015
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  3. 3
    Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids

    Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids von Nagaraj S. Nagathihalli, Yugandhar Beesetty, Wooin Lee, M. Kay Washington, Xi Chen, A. Craig Lockhart, Nipun B. Merchant

    Veröffentlicht 2014
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  4. 4
    Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma

    Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma von Daoxiang Zhang, Lin Li, Hongmei Jiang, Brett L. Knolhoff, A. Craig Lockhart, Andrea Wang‐Gillam, David G. DeNardo, Marianna B. Ruzinova, Kian‐Huat Lim

    Veröffentlicht 2016
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  5. 5
    Neoadjuvant Chemotherapy versus Chemoradiation Prior to Esophagectomy: Impact on Rate of Complete Pathologic Response and Survival in Esophageal Cancer Patients

    Neoadjuvant Chemotherapy versus Chemoradiation Prior to Esophagectomy: Impact on Rate of Complete Pathologic Response and Survival in Esophageal Cancer Patients von Pamela Samson, Clifford G. Robinson, Jeffrey D. Bradley, A. Craig Lockhart, Varun Puri, Stephen Broderick, Daniel Kreisel, Alexander S. Krupnick, G. Alexander Patterson, Bryan Meyers, Traves D. Crabtree

    Veröffentlicht 2016
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  6. 6
    Overexpression of OATP1B3 Confers Apoptotic Resistance in Colon Cancer

    Overexpression of OATP1B3 Confers Apoptotic Resistance in Colon Cancer von Wooin Lee, Abbes Belkhiri, A. Craig Lockhart, Nipun B. Merchant, Hartmut Glaeser, Elizabeth I. Harris, M. Kay Washington, Elizabeth M. Brunt, Alex Zaika, Richard B. Kim, Wael El‐Rifai

    Veröffentlicht 2008
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  7. 7
    A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer

    A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer von X. Cynthia, César Sánchez, Feng Gao, Robert J. Crowder, Michael Naughton, Timothy Pluard, Allison Creekmore, Zhanfang Guo, Jeremy Hoog, A. Craig Lockhart, Austin Doyle, Charles Erlichman, Matthew J. Ellis

    Veröffentlicht 2016
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  8. 8
    Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: a review of the National Cancer Database

    Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: a review of the National Cancer Database von Gregory Vlacich, Pamela Samson, Stephanie M. Perkins, Michael Roach, Parag J. Parikh, Jeffrey D. Bradley, A. Craig Lockhart, Varun Puri, Bryan F. Meyers, Benjamin D. Kozower, Clifford G. Robinson

    Veröffentlicht 2017
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  9. 9
    Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1

    Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1 von Lihong Wang-Bishop, Zheng Chen, Ahmed R. Gomaa, A. Craig Lockhart, Safia N. Salaria, Jialiang Wang, Keeli B. Lewis, Jeffrey Ecsedy, Kay Washington, R. Daniel Beauchamp, Wael El‐Rifai

    Veröffentlicht 2018
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  10. 10
    A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors

    A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors von Colin D. Weekes, A. Craig Lockhart, Patricia LoRusso, Elaine Murray, Erica Park, Mike Tagen, Jatinder Singh, Indrani Sarkar, Lars Müeller, Hatem Dokainish, Geoffrey I. Shapiro, Howard A. Burris

    Veröffentlicht 2020
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  11. 11
    Phase II study of neoadjuvant therapy with docetaxel, cisplatin, panitumumab, and radiation therapy followed by surgery in patients with locally advanced adenocarcinoma of the distal esophagus (ACOSOG Z4051)

    Phase II study of neoadjuvant therapy with docetaxel, cisplatin, panitumumab, and radiation therapy followed by surgery in patients with locally advanced adenocarcinoma of the dist... von A. Craig Lockhart, Carolyn E. Reed, Paul A. Decker, Bryan F. Meyers, Mark K. Ferguson, A.R. Oeltjen, Joe B. Putnam, Stephen D. Cassivi, Alberto J. Montero, Tracey E. Schefter

    Veröffentlicht 2014
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  12. 12
    Phase 1 Evaluation of [64Cu]DOTA-Patritumab to Assess Dosimetry, Apparent Receptor Occupancy, and Safety in Subjects with Advanced Solid Tumors

    Phase 1 Evaluation of [64Cu]DOTA-Patritumab to Assess Dosimetry, Apparent Receptor Occupancy, and Safety in Subjects with Advanced Solid Tumors von A. Craig Lockhart, Yongjian Liu, Farrokh Dehdashti, Richard Laforest, Joel Picus, Jennifer B. Frye, Lauren Trull, Stefanie Belanger, Madhuri Desai, Syed Mahmood, Jeanne Mendell, Michael J. Welch, Barry A. Siegel

    Veröffentlicht 2015
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  13. 13
    A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and in combination with docetaxel, in patients with advanced or refractory solid tumors

    A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and in combination with docetaxel, in patients with advanced or refractory solid tum... von Manik Amin, Susan Minton, Patricia LoRusso, Smitha Krishnamurthi, Cheryl A. Pickett, Jared Lunceford, Darcy A. Hille, David Mauro, Mark N. Stein, Andrea Wang‐Gillam, Lauren Trull, A. Craig Lockhart

    Veröffentlicht 2015
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  14. 14
    A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma

    A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma von Andrea Wang‐Gillam, Stacey M. Plambeck-Suess, Peter S. Goedegebuure, Peter O. Simon, Jonathan B. Mitchem, John R. Hornick, Steven Sorscher, Joel Picus, Rama Suresh, A. Craig Lockhart, Benjamin Tan, W. Hawkins

    Veröffentlicht 2012
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  15. 15
    Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer

    Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer von Venkataswarup Tiriveedhi, Natalia Tucker, John M. Herndon, Lijin Li, Mark Sturmoski, Matthew J. Ellis, X. Cynthia, Michael Naughton, A. Craig Lockhart, Feng Gao, Timothy P. Fleming, Peter S. Goedegebuure, Thalachallour Mohanakumar, William E. Gillanders

    Veröffentlicht 2014
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  16. 16
    Thymidylate Synthase Genotype-Directed Chemotherapy for Patients with Gastric and Gastroesophageal Junction Cancers

    Thymidylate Synthase Genotype-Directed Chemotherapy for Patients with Gastric and Gastroesophageal Junction Cancers von Laura W. Goff, Nilay Thakkar, Liping Du, Emily Chan, Benjamin Tan, Dana B. Cardin, Howard L. McLeod, Jordan Berlin, Barbara A. Zehnbauer, C. Fournier, Joel Picus, Andrea Wang‐Gillam, Wooin Lee, A. Craig Lockhart

    Veröffentlicht 2014
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  17. 17
    Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors

    Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumo... von A. Craig Lockhart, Todd M. Bauer, Charu Aggarwal, Carrie B. Lee, R. Donald Harvey, Roger B. Cohen, Farhad Sedarati, Tsz Keung Nip, Hélène M. Faessel, Ajeeta B. Dash, Bruce J. Dezube, Douglas V. Faller, Afshin Dowlati

    Veröffentlicht 2018
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  18. 18
    Pan-Cancer Efficacy of Vemurafenib in <i>BRAF</i>V600-Mutant Non-Melanoma Cancers

    Pan-Cancer Efficacy of Vemurafenib in <i>BRAF</i>V600-Mutant Non-Melanoma Cancers von Vivek Subbiah, Igor Puzanov, Jean‐Yves Blay, Ian Chau, A. Craig Lockhart, Noopur Raje, Juergen Wolf, José Baselga, Funda Meric‐Bernstam, Jason Roszik, Eli L. Diamond, Gregory J. Riely, Eric J. Sherman, Todd Riehl, Bethany Pitcher, David M. Hyman

    Veröffentlicht 2020
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  19. 19
    Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors

    Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors von A. Craig Lockhart, Mace L. Rothenberg, Jakob Dupont, Wendy Cooper, Paul Chevalier, Lars Sternås, Giliane Buzenet, Elizabeth Koehler, Jeffrey A. Sosman, Lawrence H. Schwartz, David H. Gültekin, Jason A. Koutcher, Edwin F. Donnelly, Ric Andal, Isabelle Dancy, David R. Spriggs, William P. Tew

    Veröffentlicht 2009
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  20. 20
    Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy

    Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy von Leonard B. Saltz, Lee S. Rosen, John L. Marshall, Robert J. Belt, Herbert I. Hurwitz, Sabine Eckhardt, Emily K. Bergsland, Daniel G. Haller, A. Craig Lockhart, Caio M. Rocha Lima, Xin Huang, Samuel E. DePrimo, Edna Chow‐Maneval, Richard C. Chao, Heinz Josef Lenz

    Veröffentlicht 2007
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