Resultats de la cerca - John A. Lees

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  1. 1
    Immune exclusion by naturally acquired secretory IgA against pneumococcal pilus-1

    Immune exclusion by naturally acquired secretory IgA against pneumococcal pilus-1 per Ulrike Binsker, John A. Lees, Alexandria J. Hammond, Jeffrey N. Weiser

    Publicat 2019
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  2. 2
    Accurate and fast graph-based pangenome annotation and clustering with ggCaller

    Accurate and fast graph-based pangenome annotation and clustering with ggCaller per Samuel Horsfield, Gerry Tonkin‐Hill, Nicholas J. Croucher, John A. Lees

    Publicat 2023
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  3. 3
    Adults with suspected central nervous system infection: A prospective study of diagnostic accuracy

    Adults with suspected central nervous system infection: A prospective study of diagnostic accuracy per Ula Khatib, Diederik van de Beek, John A. Lees, Matthijs C. Brouwer

    Publicat 2016
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  4. 4
    pyseer: a comprehensive tool for microbial pangenome-wide association studies

    pyseer: a comprehensive tool for microbial pangenome-wide association studies per John A. Lees, Marco Galardini, Stephen D. Bentley, Jeffrey N. Weiser, Jukka Corander

    Publicat 2018
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  5. 5
    Evaluation of phylogenetic reconstruction methods using bacterial whole genomes: a simulation based study

    Evaluation of phylogenetic reconstruction methods using bacterial whole genomes: a simulation based study per John A. Lees, Michelle Kendall, Julian Parkhill, Caroline Colijn, Stephen D. Bentley, Simon R. Harris

    Publicat 2018
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  6. 6
    RhierBAPS: An R implementation of the population clustering algorithm hierBAPS

    RhierBAPS: An R implementation of the population clustering algorithm hierBAPS per Gerry Tonkin‐Hill, John A. Lees, Stephen D. Bentley, Simon D. W. Frost, Jukka Corander

    Publicat 2018
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  7. 7
    Pneumococcal quorum sensing drives an asymmetric owner–intruder competitive strategy during carriage via the competence regulon

    Pneumococcal quorum sensing drives an asymmetric owner–intruder competitive strategy during carriage via the competence regulon per Pamela Shen, John A. Lees, Gavyn Chern Wei Bee, Sam P. Brown, Jeffrey N. Weiser

    Publicat 2018
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  8. 8
    Improved Prediction of Bacterial Genotype-Phenotype Associations Using Interpretable Pangenome-Spanning Regressions

    Improved Prediction of Bacterial Genotype-Phenotype Associations Using Interpretable Pangenome-Spanning Regressions per John A. Lees, The Tien Mai, Marco Galardini, Nicole E. Wheeler, Samuel Horsfield, Julian Parkhill, Jukka Corander

    Publicat 2020
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  9. 9
    AllTheBacteria - all bacterial genomes assembled, available and searchable

    AllTheBacteria - all bacterial genomes assembled, available and searchable per Martin Hunt, Leandro Lima, D.P. Anderson, Jane Hawkey, Wei Shen, John A. Lees, Zamin Iqbal

    Publicat 2024
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  10. 10
    Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration

    Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration per John A. Lees, Nicholas J. Croucher, David Goldblatt, François Nosten, Julian Parkhill, Claudia Turner, Paul Turner, Stephen D. Bentley

    Publicat 2017
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  11. 11
    Seamless, rapid and accurate analyses of outbreak genomic data using Split K-mer Analysis (SKA)

    Seamless, rapid and accurate analyses of outbreak genomic data using Split K-mer Analysis (SKA) per Romain Derelle, Johanna von Wachsmann, Tommi Mäklin, Joel Hellewell, Timothy Russell, Ajit Lalvani, Leonid Chindelevitch, Nicholas J. Croucher, Simon R. Harris, John A. Lees

    Publicat 2024
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  12. 12
    Seamless, rapid, and accurate analyses of outbreak genomic data using split<i>k</i>-mer analysis

    Seamless, rapid, and accurate analyses of outbreak genomic data using split<i>k</i>-mer analysis per Romain Derelle, Johanna von Wachsmann, Tommi Mäklin, Joel Hellewell, Timothy Russell, Ajit Lalvani, Leonid Chindelevitch, Nicholas J. Croucher, Simon R. Harris, John A. Lees

    Publicat 2024
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  13. 13
    Reference-free variant calling with local graph construction with ska lo (SKA)

    Reference-free variant calling with local graph construction with ska lo (SKA) per Romain Derelle, Kieran Madon, Joel Hellewell, Víctor Rodríguez-Bouza, Nimalan Arinaminpathy, Ajit Lalvani, Nicholas J. Croucher, Simon R. Harris, John A. Lees, Leonid Chindelevitch

    Publicat 2025
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  14. 14
    Fast and flexible bacterial genomic epidemiology with PopPUNK

    Fast and flexible bacterial genomic epidemiology with PopPUNK per John A. Lees, Simon R. Harris, Gerry Tonkin‐Hill, Rebecca A. Gladstone, Stephanie W. Lo, Jeffrey N. Weiser, Jukka Corander, Stephen D. Bentley, Nicholas J. Croucher

    Publicat 2019
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  15. 15
    Multiple major disease-associated clones of<i>Legionella pneumophila</i>have emerged recently and independently

    Multiple major disease-associated clones of<i>Legionella pneumophila</i>have emerged recently and independently per Sophia David, Christophe Rusniok, M. Mentasti, Laura Gómez-Valero, Simon R. Harris, P Lechat, John A. Lees, Christophe Ginévra, Philippe Glaser, Laurence Ma, Christiane Bouchier, Anthony Underwood, Sophie Jarraud, Timothy G. Harrison, Julian Parkhill, Carmen Buchrieser

    Publicat 2016
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  16. 16
    Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes

    Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes per John A. Lees, Minna Vehkala, Niko Välimäki, Simon R. Harris, Claire Chewapreecha, Nicholas J. Croucher, Pekka Marttinen, Mark R. Davies, Andrew C. Steer, Steven Y. C. Tong, Antti Honkela, Julian Parkhill, Stephen D. Bentley, Jukka Corander

    Publicat 2016
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  17. 17
    Large scale genomic analysis shows no evidence for pathogen adaptation between the blood and cerebrospinal fluid niches during bacterial meningitis

    Large scale genomic analysis shows no evidence for pathogen adaptation between the blood and cerebrospinal fluid niches during bacterial meningitis per John A. Lees, Philip H. C. Kremer, Ana Sousa Manso, Nicholas J. Croucher, Bart Ferwerda, Mercedes Valls Serón, Marco R. Oggioni, Julian Parkhill, Matthijs C. Brouwer, Arie van der Ende, Diederik van de Beek, Stephen D. Bentley

    Publicat 2016
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  18. 18
    Producing polished prokaryotic pangenomes with the Panaroo pipeline

    Producing polished prokaryotic pangenomes with the Panaroo pipeline per Gerry Tonkin‐Hill, Neil MacAlasdair, Christopher Ruis, Aaron Weimann, Gal Horesh, John A. Lees, Rebecca A. Gladstone, Stephanie W. Lo, Christopher A. Beaudoin, R. Andres Floto, Simon D. W. Frost, Jukka Corander, Stephen D. Bentley, Julian Parkhill

    Publicat 2020
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  19. 19
    Genome-wide epistasis and co-selection study using mutual information

    Genome-wide epistasis and co-selection study using mutual information per Johan Pensar, Santeri Puranen, Brian J. Arnold, Neil MacAlasdair, Juri Kuronen, Gerry Tonkin‐Hill, Maiju Pesonen, Yingying Xu, Aleksi Sipola, Leonor Sánchez-Busó, John A. Lees, Claire Chewapreecha, Stephen D. Bentley, Simon R. Harris, Julian Parkhill, Nicholas J. Croucher, Jukka Corander

    Publicat 2019
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  20. 20
    Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant <i>Staphylococcus aureus</i>

    Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant <i>Staphylococcus aureus</i> per Richard Copin, William E. Sause, Yi Fulmer, Divya Balasubramanian, Sophie Dyzenhaus, Jamil Ahmed, Krishan Kumar, John A. Lees, Anna Stachel, Jason C. Fisher, Karl Drlica, Michael Phillips, Jeffrey N. Weiser, Paul J. Planet, Anne‐Catrin Uhlemann, Deena R. Altman, Robert Sebra, Harm van Bakel, Jennifer Lighter, Victor J. Torres, Bo Shopsin

    Publicat 2019
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