Canlyniadau Chwilio - Gregory H. Bird

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  1. 1
    Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

    Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress gan Loren D. Walensky, Gregory H. Bird

    Cyhoeddwyd 2014
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  2. 2
    Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting

    Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting gan Gregory H. Bird, W. Christian Crannell, Loren D. Walensky

    Cyhoeddwyd 2011
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  3. 3
    Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains

    Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains gan Gregory H. Bird, Federico Bernal, Kenneth L. Pitter, Loren D. Walensky

    Cyhoeddwyd 2008
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  4. 4
    BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX

    BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX gan Evripidis Gavathiotis, Denis E. Reyna, Marguerite L. Davis, Gregory H. Bird, Loren D. Walensky

    Cyhoeddwyd 2010
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  5. 5
    Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting

    Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting gan Franziska Wachter, Ann M. Morgan, Marina Godes, Rida Mourtada, Gregory H. Bird, Loren D. Walensky

    Cyhoeddwyd 2016
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  6. 6
    Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies

    Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies gan Gregory H. Bird, A. Irimia, Gilad Ofek, Peter D. Kwong, Ian A. Wilson, Loren D. Walensky

    Cyhoeddwyd 2014
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  7. 7
    Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices

    Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices gan Gregory H. Bird, Emanuele Mazzola, Kwadwo Opoku-Nsiah, Margaret Lammert, Marina Godes, Donna Neuberg, Loren D. Walensky

    Cyhoeddwyd 2016
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  8. 8
    Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer

    Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer gan Woojin Kim, Gregory H. Bird, Tobias Neff, Guoji Guo, Marc A. Kerenyi, Loren D. Walensky, Stuart H. Orkin

    Cyhoeddwyd 2013
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  9. 9
    Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor

    Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor gan Edward P. Harvey, Hyuk‐Soo Seo, Rachel M. Guerra, Gregory H. Bird, Sirano Dhe‐Paganon, Loren D. Walensky

    Cyhoeddwyd 2017
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  10. 10
    Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3

    Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 gan Amanda Edwards, Evripidis Gavathiotis, James L. LaBelle, Craig R. Braun, Kwadwo Opoku-Nsiah, Gregory H. Bird, Loren D. Walensky

    Cyhoeddwyd 2013
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  11. 11
    A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators

    A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators gan Benjamin Szlyk, Craig R. Braun, Sanda Ljubicic, Elaura Patton, Gregory H. Bird, Mayowa Osundiji, Franz M. Matschinsky, Loren D. Walensky, Nika N. Danial

    Cyhoeddwyd 2013
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  12. 12
    Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

    Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic gan Gregory H. Bird, Navid Madani, Alisa F. Perry, Amy M. Princiotto, Jeffrey G. Supko, Xiaoying He, Evripidis Gavathiotis, Joseph Sodroski, Loren D. Walensky

    Cyhoeddwyd 2010
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  13. 13
    Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

    Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices gan Elizaveta S. Leshchiner, Andrey A. Parkhitko, Gregory H. Bird, James Luccarelli, Joseph A. Bellairs, Silvia Escudero, Kwadwo Opoku-Nsiah, Marina Godes, Norbert Perrimon, Loren D. Walensky

    Cyhoeddwyd 2015
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  14. 14
    Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells

    Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells gan Raheleh Rezaei Araghi, Gregory H. Bird, Jeremy Ryan, J.M. Jenson, Marina Godes, Jonathan R. Pritz, Robert A. Grant, Anthony Letai, Loren D. Walensky, Amy E. Keating

    Cyhoeddwyd 2018
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  15. 15
    BAX activation is initiated at a novel interaction site

    BAX activation is initiated at a novel interaction site gan Evripidis Gavathiotis, Motoshi Suzuki, Marguerite L. Davis, Kenneth L. Pitter, Gregory H. Bird, Samuel G. Katz, Ho-Chou Tu, Hyungjin Kim, Emily H. Cheng, Nico Tjandra, Loren D. Walensky

    Cyhoeddwyd 2008
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  16. 16
    Allosteric inhibition of antiapoptotic MCL-1

    Allosteric inhibition of antiapoptotic MCL-1 gan Susan Lee, Thomas E. Wales, Silvia Escudero, Daniel T. Cohen, James Luccarelli, Catherine G Gallagher, Nicole A. Cohen, Annissa J. Huhn, Gregory H. Bird, John R. Engen, Loren D. Walensky

    Cyhoeddwyd 2016
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  17. 17
    Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

    Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration gan Sarah E. Pease-Raissi, Maria F. Pazyra‐Murphy, Yihang Li, Franziska Wachter, Yusuke Fukuda, Sara J. Fenstermacher, Lauren A. Barclay, Gregory H. Bird, Loren D. Walensky, Rosalind A. Segal

    Cyhoeddwyd 2017
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  18. 18
    Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection

    Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection gan Gregory H. Bird, Sandhya Boyapalle, Terianne Wong, Kwadwo Opoku-Nsiah, Raminder Bedi, W. Christian Crannell, Alisa F. Perry, Huy Duc Nguyen, Viviana Sampayo, Ankita Devareddy, Subhra Mohapatra, Shyam S. Mohapatra, Loren D. Walensky

    Cyhoeddwyd 2014
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  19. 19
    A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

    A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers gan James L. LaBelle, Samuel G. Katz, Gregory H. Bird, Evripidis Gavathiotis, Michelle L. Stewart, Chelsea E. Lawrence, Jill K. Fisher, Marina Godes, Kenneth L. Pitter, Andrew L. Kung, Loren D. Walensky

    Cyhoeddwyd 2012
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  20. 20
    Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets

    Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets gan Accalia Fu, Lara van Rooyen, Lindsay Evans, Nina Armstrong, Daina Avizonis, Tatsuya Kin, Gregory H. Bird, Anita Reddy, Edward T. Chouchani, Marc Liesa, Loren D. Walensky, A. M. James Shapiro, Nika N. Danial

    Cyhoeddwyd 2021
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